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On-demand PresentationWhat is the hydrodynamic radius?In dynamic light scattering (DLS) intensity fluctuations of the scattering light are analyzed. The fluctuation rate is related to the diffusion coefficient of the scattering species. The radius of a hard sphere with the same diffusion coefficient is the hydrodynamic radius RH. Additional radii such as the rotation radius, a mass radius and a radius of gyration are also defined. These different radii are shown for a lysozyme molecule. Comparison of the hydrodynamic radius of larger proteins (insulin, immunoglobulin G, thyroglobulin) shows the range of values for biomolecules.
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